Fortune I derive from pluckiest brat (4)
I believe the answer is:
pest
'brat' is the definition.
(I've seen this in another clue)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for pest that I've seen before include "Annoying creature" , "Troublesome person" , "Aphis" , "A nuisance - step on it" , "Destructive insect or nuisance" .)