Frame of mind reversed the lot (4)
I believe the answer is:
mood
'frame of mind' is the definition.
(I've seen this in another clue)
'reversed the lot' is the wordplay.
'reversed' becomes 'moo' (I can't justify this - if you can you should give a lot more credence to this answer).
'the lot' becomes 'd'.
'moo'+'d'='MOOD'
Can you help me to learn more?
(Other definitions for mood that I've seen before include "State of mind, humour" , "Humour - bad temper" , "An atmosphere of doom" , "melancholy" , "Depression" .)