"Frasier" setting (7)
I believe the answer is:
seattle
'frasier setting' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for seattle that I've seen before include "US Pacific seaport" , "American city" , "US Pacific port" , "US West coast port" , "Largest city in the state of Washington" .)