French president fires Republican, one of his reds perhaps? (5)
I believe the answer is:
macon
'one of his reds perhaps?' is the definition.
Although both the answer and definition are singular nouns, I can't see how they can define each other.
'french president fires republican' is the wordplay.
'french president' becomes 'macron' (Emmanuel Macron).
'fires' suggests deleting specific letters.
'republican' becomes 'r' (abbreviation).
'macron' with 'r' taken out is 'MACON'.
(Other definitions for macon that I've seen before include "A heavy Burgundy" , "red" , "Wandering (knight)" , "Dry white Burgundy wine" , "French wine district" .)