Frenzied female in charge full of bluster (7)
I believe the answer is:
frantic
'frenzied' is the definition.
(I know that frenzied can be written as frantic)
'female in charge full of bluster' is the wordplay.
'female' becomes 'f' (abbreviation).
'in charge' becomes 'ic' (abbreviation for 'in charge').
'full of' is an insertion indicator.
'bluster' becomes 'rant' (I've seen this in another clue).
'f'+'ic'='fic'
'fic' enclosing 'rant' is 'FRANTIC'.
(Other definitions for frantic that I've seen before include "Wild - frenzied" , "Overwrought" , "Desperate with worry" , "'Unrestrained, overly agitated (7)'" , "Distracted" .)