Friend in France upset about mate being in Africa (6)
I believe the answer is:
impala
'being in africa' is the definition.
(type of antelope native to Africa)
'friend in france upset about mate' is the wordplay.
'friend in france' becomes 'ami' ('friend' in French).
'upset' says the letters should be written backwards.
'about' is an insertion indicator.
'mate' becomes 'pal' (I've seen this before).
'ami' written backwards gives 'ima'.
'ima' going around 'pal' is 'IMPALA'.
(Other definitions for impala that I've seen before include "horny creature" , "'African antelope, takes great leaps (6)'" , "Antelope with lyre-shaped horns" , "horny type" , "Breed of antelope" .)