Friend rejected advice and consumed pulse (9)
I believe the answer is:
palpitate
'pulse' is the definition.
(thesaurus)
'friend rejected advice and consumed' is the wordplay.
'friend' becomes 'pal' (pal is a kind of friend).
'rejected' is a reversal indicator.
'advice' becomes 'tip' (I've seen this before).
'and' is a charade indicator (letters next to each other).
'consumed' becomes 'ate' (eating is a kind of consuming).
'tip' backwards is 'pit'.
'pal'+'pit'+'ate'='PALPITATE'
(Other definitions for palpitate that I've seen before include "Shake, tremble" , "flutter" , "Beat abnormally quickly" , "Rapidly beat" , "quiver" .)