From Guatemala, I sense a general problem (7)
I believe the answer is:
malaise
'a general problem' is the definition.
'from guatemala i sense' is the wordplay.
'from' says the answer is hidden in the clue.
'MALAISE' is hidden within 'guatemala i sense'.
(Other definitions for malaise that I've seen before include "Disquiet" , "General feeling of discomfort" , "General feeling of unease or illness" , "Feeling of impending illness" , "Uneasy feeling" .)