Fruit loaf's split between hands (5)
I believe the answer is:
melon
'fruit' is the definition.
(I know that melon is a type of fruit)
'loaf's split between hands' is the wordplay.
'loaf's split' becomes 'lo' (I can't justify this - if you can you should believe this answer much more).
'between' indicates putting letters inside.
'hands' becomes 'men' (synonyms).
'lo' placed into 'men' is 'MELON'.
Can you help me to learn more?
(Other definitions for melon that I've seen before include "Gourdlike fruit" , "Ogen or cantaloupe, for instance" , "Type of pepo" , "Fruit - lemon (anag)" , "Killing" .)