Fruits' regrettable transience (10)
I believe the answer is:
nectarines
'fruits'' is the definition.
(nectarine is a kind of fruit)
'regrettable transience' is the wordplay.
'regrettable' indicates anagramming the letters.
'transience' anagrammed gives 'NECTARINES'.
I've seen this clue in The Everyman puzzle in The Observer.
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