Frustrate man's right to change (9)
I believe the answer is:
hamstring
'frustrate' is the definition.
(hamstringing is a kind of frustrating)
'man's right to change' is the wordplay.
'to change' indicates an anagram.
'mans'+'right'='mansright'
'mansright' with letters rearranged gives 'HAMSTRING'.
(Other definitions for hamstring that I've seen before include "hamper" , "Tendons at back of the knee" , "Tendon behind the knee" , "Thwart, severely restrict" , "Impede" .)