Fuel favoured a lot of motion on wheels (6)
I believe the answer is:
petrol
'fuel' is the definition.
(petrol is a kind of fuel)
'favoured a lot of motion on wheels' is the wordplay.
'favoured' becomes 'pet' (as in a pet project).
'a lot of' means to remove the first letter.
'motion' becomes 'ko' (KO is an example).
'on' is an insertion indicator.
'wheels' becomes 'rl' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'ko' with its first letter taken off is 'o'.
'o' put into 'rl' is 'rol'.
'pet'+'rol'='PETROL'
Can you help me to learn more?
(Other definitions for petrol that I've seen before include "Common car fuel" , "Common motor fuel" , "Fuel for road vehicles" , "Liquid fuel" , "Mineral oil refined as fuel" .)