Fully sensitive to a vile manoeuvre (5)
I believe the answer is:
alive
'fully sensitive' is the definition.
'alive' can be an answer for 'sensitive' (similar in meaning). I am not sure about the 'fully' bit.
'a vile manoeuvre' is the wordplay.
'manoeuvre' indicates an anagram.
'vile' anagrammed gives 'live'.
'a'+'live'='ALIVE'
'to' acts as a link.
Can you help me to learn more?
(Other definitions for alive that I've seen before include "Breathing, existing" , "Active - living" , "Aware" , "Still with us" , "Existing - vigorous" .)