Fur on one animal (5)
I believe the answer is:
coati
'animal' is the definition.
(mammal of Central and South America)
'fur on one' is the wordplay.
'fur' becomes 'coat' (an animal's coat).
'on' is a charade indicator (letters next to each other).
'one' becomes 'I' (Roman numeral).
'coat'+'i'='COATI'
(Other definitions for coati that I've seen before include "South American animal" , "carnivore from South America" , "beast" , "American mammal related to raccoon" , "omnivorous mammal" .)