Further from Rome? (4)
I believe the answer is:
more
'further' is the definition.
('more' can be a synonym of 'further')
'from rome?' is the wordplay.
'from' is an anagram indicator (from the letters).
'rome' with letters rearranged gives 'MORE'.
(Other definitions for more that I've seen before include "To a greater extent" , "Greater quantity or number" , "A greater amount" , "See 9" , "victim of Henry" .)