Fury - big-time (7)
I believe the answer is:
megaera
'fury' is the definition.
(thesaurus)
'big-time' is the wordplay.
'big' becomes 'mega' (I've seen this before).
'time' becomes 'era' (I've seen this before).
'mega'+'era'='MEGAERA'
(Another definition for megaera that I've seen is " One of the Furies".)
I've seen this clue in The Independent.
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