Fuss about drunken rep causing wreck (7)
I believe the answer is:
torpedo
'wreck' is the definition.
(I've seen this before)
'fuss about drunken rep' is the wordplay.
'fuss' becomes 'todo' (I've seen this before).
'about' is an insertion indicator.
'drunken' indicates an anagram.
'rep' is an anagram of 'rpe'.
'todo' placed around 'rpe' is 'TORPEDO'.
'causing' is the link.
(Other definitions for torpedo that I've seen before include "Missile form a submarine" , "Missile fired from underwater submarine" , "Underwater bomb" , "Such as could sink" , "Explosive missile from submarine" .)