Fuss as the two meet monarch (6)
I believe the answer is:
bother
'fuss' is the definition.
('bother' can be a synonym of 'fuss')
'the two meet monarch' is the wordplay.
'the two' becomes 'both' ('both' can be a synonym of 'the two').
'meet' says to put letters next to each other.
'monarch' becomes 'er' (abbreviation for Elizabeth Regina).
'both'+'er'='BOTHER'
'as' is the link.
(Other definitions for bother that I've seen before include "Fuss and irritant" , "Worry, disturb" , "Fuss and nuisance" , "Discommode, annoy" , "Annoy or pester" .)