Garment from southern India a queen wears (4)
I believe the answer is:
sari
'garment' is the definition.
(sari is a kind of garment)
'from southern india a queen wears' is the wordplay.
'from' is an anagram indicator (from the letters).
'southern' becomes 's' (abbreviation).
'india' becomes 'i' (phonetic alphabet: alpha, bravo, charlie etc.).
'queen' becomes 'r' (abbreviation for regina, e.g. in ER ).
'wears' is an insertion indicator.
's'+'i'+'a'='sia'
'sia' with letters rearranged gives 'sai'.
'sai' placed around 'r' is 'SARI'.
(Other definitions for sari that I've seen before include "Something worn" , "Traditional Indian women's dress" , "habit" , "Asian dress" , "Hindu female garment" .)