Get comfortable around a city (7)
I believe the answer is:
seattle
'city' is the definition.
(I know that Seattle is a city)
'get comfortable around a' is the wordplay.
'get comfortable' becomes 'settle' (I've seen this before).
'around' indicates putting letters inside.
'settle' enclosing 'a' is 'SEATTLE'.
(Other definitions for seattle that I've seen before include "City of north-west USA" , "Let's eat at this US city" , "somewhere in Washington" , "Port of north-west USA" , "? American seaport" .)