Get on with female causing harm (6)
I believe the answer is:
damage
'harm' is the definition.
(synonyms)
'get on with female' is the wordplay.
'get on' becomes 'age' (synonyms).
'with' says to put letters next to each other.
'female' becomes 'dam' (dam is a kind of female).
'age' put after 'dam' is 'DAMAGE'.
'causing' acts as a link.
(Other definitions for damage that I've seen before include "Cost (slang)" , "Impairment, injury" , "Impair or cause injury to" , "Physical harm" , "'Deface, impair (6)'" .)