Get stuck into a hefty slice (5)
I believe the answer is:
wedge
'slice' is the definition.
(I've seen this before)
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for wedge that I've seen before include "Device eg to keep door open" , "Splitting device" , "Piece of wood thick at one end, thin at other" , "Chock" , "Jam" .)