Gets along well with this weird, initially irritating nob (4,2,3)
I believe the answer is:
hits it off
'gets along well' is the definition.
I know nothing about this answer so I cannot tell whether this works.
'this weird initially irritating nob' is the wordplay.
'weird' indicates an anagram.
'initially' indicates taking the first letters.
'nob' becomes 'toff' (synonyms).
The first letter of 'irritating' is 'i'.
'this' is an anagram of 'hits'.
'hits'+'i'+'toff'='HITS IT OFF'
'with' acts as a link.
Can you help me to learn more?
(Another definition for hits it off that I've seen is " Clicks".)