Giant dog breed (7)
I believe the answer is:
mastiff
(Other definitions for mastiff that I've seen before include "Strong breed of dog" , "Big dog" , "Hound" , "Powerful, smooth-coated dog used for security work" , "one of his best friends?" .)
I believe the answer is:
mastiff
(Other definitions for mastiff that I've seen before include "Strong breed of dog" , "Big dog" , "Hound" , "Powerful, smooth-coated dog used for security work" , "one of his best friends?" .)