Ginger wine gets male dead drunk (3-6)
I believe the answer is:
red-headed
'ginger' is the definition.
(I've seen this before)
'wine gets male dead drunk' is the wordplay.
'wine' becomes 'red' (red wine is a kind of wine**).
'gets' is a charade indicator (letters next to each other).
'male' becomes 'he'.
'drunk' indicates an anagram.
'dead' is an anagram of 'aded'.
'red'+'he'+'aded'='RED-HEADED'
(Other definitions for red-headed that I've seen before include "Ginger" , "Like Prince Harry on top" .)