Girl starts off at Marshalsea yard (3)
I believe the answer is:
amy
'girl' is the definition.
'starts off at marshalsea yard' is the wordplay.
'starts off' indicates taking the first letters.
The initial letters of 'at marshalsea yard' is 'AMY'.
(Other definitions for amy that I've seen before include "-- Johnson, female flyer" , "Girl's name; 3 dn (anag.)" , "so-called little woman" , "- Johnson, Eng. aviatrix" , "--, Johnson, solo flyer" .)