Girl upon wings of drake, duck (5)
I believe the answer is:
evade
'duck' is the definition.
('evade' can be a synonym of 'duck')
'girl upon wings of drake' is the wordplay.
'girl' becomes 'eva' (**).
'upon' is a charade indicator (letters next to each other).
'wings of' says to hollow out the word (remove centre letters) (letters on the two wings removed).
'drake' with its middle taken out is 'de'.
'eva'+'de'='EVADE'
(Other definitions for evade that I've seen before include "Slyly escape" , "temptress conveying commercial message" , "Dodge - prevaricate" , "Dodge (taxes)" , "Escape paying (tax)" .)