Give a wide berth to high region (6)
I believe the answer is:
ignore
'give a wide berth to' is the definition.
I can't judge whether this definition defines the answer.
'high region' is the wordplay.
'high' is an anagram indicator (like drunk).
'region' is an anagram of 'IGNORE'.
Can you help me to learn more?
(Other definitions for ignore that I've seen before include "bypass" , "Pass over" , "Fail to observe" , "Deliberately overlook" , "Brush off" .)