Give most excellent response to pain? (6)
I believe the answer is:
bestow
'give' is the definition.
(I know that bestow is a more specific form of the action give)
'most excellent response to pain?' is the wordplay.
I cannot quite understand how this works, but
'to' is found in the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for bestow that I've seen before include "'Confer, present (6)'" , "Confer or award" , "Present, donate" , "Confer - impart" , "Award, present as a gift" .)