Give out to Edna (6)
I believe the answer is:
donate
'give' is the definition.
(I know that donate is a more specific form of the action give)
'out to edna' is the wordplay.
'out' indicates an anagram.
'to'+'edna'='toedna'
'toedna' with letters rearranged gives 'DONATE'.
(Other definitions for donate that I've seen before include "Give to a charity or good cause" , "Give - present" , "Muhammad -, US boxer" , "Give money to charity" , "Give (eg to charity)" .)