Give up blocking genuine compensation (8)
I believe the answer is:
requital
'compensation' is the definition.
(I've seen this before)
'give up blocking genuine' is the wordplay.
'give up' becomes 'quit' (synonyms).
'blocking' indicates putting letters inside.
'genuine' becomes 'real' (associated in meaning).
'quit' put within 'real' is 'REQUITAL'.
(Other definitions for requital that I've seen before include "Payment in return" , "reward" , "Amends" , "Satisfactory compensation" , "Recompense" .)