Give up; desert (7)
I believe the answer is:
abandon
This clue is a double definition.
'give up' is the first definition.
(synonyms)
'desert' is the second definition.
(synonyms)
(Other definitions for abandon that I've seen before include "Stop" , "Desert; intemperance" , "Junk" , "Desert, strand" , "Desert or yield without restraint" .)