Given alcohol, Charlie tucked in and made a face (6)
I believe the answer is:
winced
'made a face' is the definition.
(wincing is a kind of making a face)
'given alcohol charlie tucked in' is the wordplay.
'given alcohol' becomes 'wined' (as in wining and dining).
'charlie' becomes 'C' (phonetic alphabet: alpha, bravo, charlie etc.).
'tucked in' is an insertion indicator.
'wined' placed around 'c' is 'WINCED'.
'and' acts as a link.
(Other definitions for winced that I've seen before include "Grimaced slightly" , "Made slight involuntary movement from pain or embarrassment" , "Flinched, cringed" , "Flinched, made a face" .)