Globe, Shakespeare played initially in this place (6)
I believe the answer is:
sphere
'globe' is the definition.
(thesaurus)
'shakespeare played initially in this place' is the wordplay.
'initially' suggests taking the first letters.
'in this place' becomes 'here' ('here' can be a synonym of 'in this place').
The initial letters of 'shakespeare played' is 'sp'.
'sp'+'here'='SPHERE'
(Other definitions for sphere that I've seen before include "Area of activity" , "Globe or domain" , "Ball shape" , "Shape of the Earth" , "Round solid figure with every point on its surface equidistant from its centre" .)