Go back again with a man-eater (4)
I believe the answer is:
ogre
'a man-eater' is the definition.
(I've seen this before)
'go back again' is the wordplay.
'back' says the letters should be written backwards.
'again' becomes 're' (prefix meaning 'again').
'go' reversed gives 'og'.
'og'+'re'='OGRE'
'with' acts as a link.
(Other definitions for ogre that I've seen before include "Fierce giant" , "Bugbear" , "ugly one" , "Man-eating monster of fairy tales" , "Terrifying man" .)