Go back again with a man-eater (4)
I believe the answer is:
ogre
'a man-eater' is the definition.
(I've seen this before)
'go back again' is the wordplay.
'back' says the letters should be written in reverse.
'again' becomes 're'.
'go' written backwards gives 'og'.
'og'+'re'='OGRE'
'with' is the link.
(Other definitions for ogre that I've seen before include "Fierce giant" , "Bugbear" , "ugly one" , "Man-eating monster of fairy tales" , "Terrifying man" .)