Go crazy when upset (4)
I believe the answer is:
stab
'go' is the definition.
(both can mean an attempt)
'crazy when upset' is the wordplay.
'crazy' becomes 'bats' (I've seen this before).
'when upset' shows that the letters should be reversed in order (in a down clue - set, written, up).
'bats' back-to-front is 'STAB'.
(Other definitions for stab that I've seen before include "Twinge; guess" , "Run through - essay" , "Try - skewer" , "Jab" , "Pierce with a dagger" .)