Go, shifty varlet! (6)
I believe the answer is:
travel
'go' is the definition.
(I know that travel is a type of go)
'shifty varlet' is the wordplay.
'shifty' is an anagram indicator.
'varlet' with letters rearranged gives 'TRAVEL'.
(Other definitions for travel that I've seen before include "Go on a journey" , "treatment for a narrow mind?" , "Go on a trip" , "Varlet (anag.)" , "It is said to broaden the mind" .)