Going back on decision to have transplant operation? (6,2,5)
I believe the answer is:
change of heart
'going back on decision' is the definition.
I don't understand the rest of the clue.
(Other definitions for change of heart that I've seen before include "Attitude shift" , "Having a different view" , "Profound shift in outlook" , "rethink" , "Profound alteration in outlook or opinion" .)