Graduate from university in Manali, prepared to leave institute (6)
I believe the answer is:
alumna
'graduate' is the definition.
(synonyms)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for alumna that I've seen before include "Harvard graduate" , "Female former pupil" , "Manual (anag) - old girl" , "Female graduate" , "She studied" .)