Gran turned me off thong? (12)
I believe the answer is:
undergarment
'thong?' is the definition.
(thong is a type of underwear)
'gran turned me off' is the wordplay.
'off' indicates anagramming the letters.
'gran'+'turned'+'me'='granturnedme'
'granturnedme' with letters rearranged gives 'UNDERGARMENT'.
(Other definitions for undergarment that I've seen before include "Eg, vest or pants" , "drawers, maybe" , "Pants perhaps" , "Item of clothing worn next to the skin" .)