— Grande (3)
I believe the answer is:
rio
'grande' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for rio that I've seen before include "Spanish word for river" , "Port, -- de Janeiro" , "Flying Down to -, Astaire, Rogers film" , "Manchester United player in South American city, in short?" , "The ... Grande borders Texas and Mexico" .)