Grandma, affectionately
I believe the answer is:
nana
'grandma affectionately' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for nana that I've seen before include "Grandmother - dog in Peter Pan" , "Informal grandmother" , "Relative" , "Zola tale of a courtesan" , "Old woman" .)