Great game is played (4)
I believe the answer is:
mega
'great' is the definition.
(old-fashioned UK slang for 'very good')
'game is played' is the wordplay.
'is played' is an anagram indicator (letters playing around).
'game' with letters rearranged gives 'MEGA'.
(Other definitions for mega that I've seen before include "Very large (prefix)" , "Great American" , "Terrific" , "Informally great or large" , "Fantastic!" .)