Great to be wasted! (4)
I believe the answer is:
high
I believe this is a double definition.
'great' is the first definition.
(similar in meaning)
'be wasted' is the second definition.
(wasted can mean high on drugs)
'to' is the link.
(Other definitions for high that I've seen before include "Drunk; anticyclone" , "having senior ranking?" , "At altitude" , "Hypertension" , "Shrill" .)