Greeting given saints? Unlikely! (4)
I believe the answer is:
hiss
'greeting given saints? unlikely' is the definition.
I can't judge whether this definition defines the answer.
'greeting given saints?' is the wordplay.
'greeting' becomes 'hi' (hi is a kind of greeting).
'given' means one lot of letters go next to another.
'saints?' becomes 'ss' (an abbreviation for saint written twice).
'hi'+'ss'='HISS'
Can you help me to learn more?
(Other definitions for hiss that I've seen before include "Sharp sound of disapproval" , "Audio interference" , "Snake's sibilant sound" , "Jeer" , "Make sibilant sound like snake" .)