Gristle first removed about bone by Clyde’s neighbour (9)
I believe the answer is:
granville
'gristle first removed' is the definition.
I can't judge whether this defines the answer.
'bone by clyde's neighbour' is the wordplay.
I cannot really understand how this works, but
'bone' could be 'anvil' (anvil is a kind of bone) and 'anvil' is present in the answer.
This may be the basis of the clue (or it may be nonsense).
'about' is the link.
Can you help me to learn more?
(Other definitions for granville that I've seen before include "Sir - Bantock, British composer" , "Ex-foreign secretary" .)