Group of loudmouths on strike (3)
I believe the answer is:
out
'on strike' is the definition.
(I've seen this before)
'group of loudmouths' is the wordplay.
'group of' indicates the answer is hidden within the clue (group of letters from the clue).
'OUT' is hidden within 'loudmouths'.
(Other definitions for out that I've seen before include "Elsewhere -- unfashionable" , "No longer imprisoned" , "Away; into public domain" , "Means of escape" , "Escaped" .)