Group of stars runs into Spanish port (5)
I believe the answer is:
virgo
'group of stars' is the definition.
(I know that Virgo is a constellation)
'runs into spanish port' is the wordplay.
'runs' becomes 'r' (cricket abbreviation).
'into' is an insertion indicator.
'spanish port' becomes 'vigo' (port in Spain).
'r' placed inside 'vigo' is 'VIRGO'.
(Other definitions for virgo that I've seen before include "Large constellation between Leo and Libra" , "number of stars" , "A constellation, a cluster" , "Sixth sign of zodiac" , "House" .)