Grumble millions express (6)
I believe the answer is:
mutter
'grumble' is the definition.
(synonyms)
'millions express' is the wordplay.
'millions' becomes 'm' (abbreviation).
'express' becomes 'utter' (synonyms).
'm'+'utter'='MUTTER'
(Other definitions for mutter that I've seen before include "Mumble" , "Speak indistinctly or grumble" , "Speak quietly and indistinctly" , "Talk under one's breath" , "carp, > grouse and > beef" .)