Guide drug seller quietly away (5)
I believe the answer is:
usher
'guide' is the definition.
(ushering is a kind of guiding)
'drug seller quietly away' is the wordplay.
'drug seller' becomes 'pusher'.
'quietly' becomes 'p' (p for piano and quiet).
'away' suggests deleting specific letters.
'pusher' with 'p' removed is 'USHER'.
(Other definitions for usher that I've seen before include "One escorts people to seats" , "Person whose job is to conduct others" , "Court or parliamentary official" , "Show (in or out); doorkeeper" , "Doorkeeper, escort" .)